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PHI-1 Interacts with the Catalytic Subunit of Myosin Light Chain Phosphatase to Produce a Ca(2+) Independent Increase in MLC(20) Phosphorylation and Force in Avian Smooth Muscle

In avian smooth muscles, GTPγS produces a Rho kinase mediated increase in PHI-1 phosphorylation and force, but whether this correlation is causal is unknown. We examined the effect of phosphorylated PHI-1 (P-PHI-1) on force and MLC(20) phosphorylation at a constant [Ca(2+)]. P-PHI-1, but not PHI-1,...

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Main Authors: El-Toukhy, Amr, Given, Allison M, Ogut, Ozgur, Brozovich, Frank V
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698950/
https://ncbi.nlm.nih.gov/pubmed/17022978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2006.09.035
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