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Sphingosine 1-phosphate as a regulator of osteoclast differentiation and osteoclast–osteoblast coupling
Sphingosine 1-phosphate (S1P), produced by sphingosine kinase (SPHK), acts both by intracellular and extracellular modes. We evaluated the role of SPHK1 and S1P in osteoclastogenesis using bone marrow-derived macrophage (BMM) single and BMM/osteoblast coculture systems. In BMM single cultures, the o...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1698879/ https://ncbi.nlm.nih.gov/pubmed/17124500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601430 |
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