A Critical Role for Peroxisomal Proliferator-Activated Receptor-α Nuclear Receptors in the Development of Cardiomyocyte Degeneration and Necrosis

Peroxisomal proliferator-activated receptor (PPAR)-α is a ligand-activated transcriptional factor that regulates genes involved in lipid metabolism and energy homeostasis. PPAR-α activators, including fibrates, have been used to treat dyslipidemia for several decades. In contrast to their known effe...

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Detalhes bibliográficos
Main Authors: Pruimboom-Brees, Ingrid, Haghpassand, Mehrdad, Royer, Lori, Brees, Dominique, Aldinger, Charles, Reagan, William, Singh, Jatinder, Kerlin, Roy, Kane, Christopher, Bagley, Scott, Hayward, Cheryl, Loy, James, O’Brien, Peter, Francone, Omar L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698838/
https://ncbi.nlm.nih.gov/pubmed/16936252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.051110
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