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Roles of Saccharomyces cerevisiae DNA polymerases Polη and Polζ in response to irradiation by simulated sunlight

Sunlight causes lesions in DNA that if unrepaired and inaccurately replicated by DNA polymerases yield mutations that result in skin cancer in humans. Two enzymes involved in translesion synthesis (TLS) of UV-induced photolesions are DNA polymerase η (Polη) and polymerase ζ (Polζ), encoded by the RA...

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Udgivet i:Nucleic Acids Res
Principais autores: Kozmin, Stanislav G., Pavlov, Youri I., Kunkel, Thomas A., Sage, Evelyne
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
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Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC169879/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12888515/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg489
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