Nitric Oxide Is an Important Mediator of Renal Tubular Epithelial Cell Death in Vitro and in Murine Experimental Hydronephrosis

Macrophages play a pivotal role in tissue injury and fibrosis during renal inflammation. Although macrophages may induce apoptosis of renal tubular epithelial cells, the mechanisms involved are unclear. We used a microscopically quantifiable co-culture assay to dissect the cytotoxic interaction betw...

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Detalhes bibliográficos
Main Authors: Kipari, Tiina, Cailhier, Jean-Francois, Ferenbach, David, Watson, Simon, Houlberg, Kris, Walbaum, David, Clay, Spike, Savill, John, Hughes, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698789/
https://ncbi.nlm.nih.gov/pubmed/16877341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050964
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