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Low pH enhances Sp1 DNA binding activity and interaction with TBP

Sp1 is involved in the regulation of a wide variety of genes, including housekeeping genes and genes involved in tumor growth. Sp1 is a member of the C2-H2 zinc-finger family and is important for protection against cellular acidosis in cells that grow under hypoxic or acidic conditions, such as tumo...

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Bibliografiske detaljer
Main Authors: Torigoe, Takayuki, Izumi, Hiroto, Yoshida, Yoichiro, Ishiguchi, Hiroshi, Okamoto, Takashi, Itoh, Hideaki, Kohno, Kimitoshi
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC169877/
https://ncbi.nlm.nih.gov/pubmed/12888513
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