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The Role of Nicotinamide Adenine Dinucleotide Phosphate Oxidase-Derived Reactive Oxygen Species in the Acquisition of Metastatic Ability of Tumor Cells

We examined the role of phagocyte-derived oxygen radicals in tumor cell acquisition of metastatic phenotype by comparing gp91(phox−/−) mice and C57BL/6J wild-type (WT) mice. The gp91(phox−/−) mouse is deficient in the gp91(phox) gene, an essential subunit of the phagocyte nicotinamide adenine dinucl...

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Autori principali: Okada, Futoshi, Kobayashi, Masanobu, Tanaka, Hiroki, Kobayashi, Tokushige, Tazawa, Hiroshi, Iuchi, Yoshihito, Onuma, Kunishige, Hosokawa, Masuo, Dinauer, Mary C., Hunt, Nicholas H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698756/
https://ncbi.nlm.nih.gov/pubmed/16816381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060073
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