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Overexpression of the Transcription Factor GATA-3 Enhances the Development of Pulmonary Fibrosis

Recent studies have demonstrated that Th2 cytokines, such as interleukin-4 and interleukin-13, enhance fibrotic processes by activating fibroblast proliferation and collagen production, whereas interferon-γ, a Th1 cytokine, inhibits these processes. Th1 and Th2 cells both differentiate from common T...

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Détails bibliographiques
Auteurs principaux: Kimura, Toru, Ishii, Yukio, Yoh, Keigyou, Morishima, Yuko, Iizuka, Takashi, Kiwamoto, Takumi, Matsuno, Yosuke, Homma, Shinsuke, Nomura, Akihiro, Sakamoto, Tohru, Takahashi, Satoru, Sekizawa, Kiyohisa
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698754/
https://ncbi.nlm.nih.gov/pubmed/16816364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.051160
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