Transcriptional Up-Regulation and Activation of Initiating Caspases in Experimental Glaucoma

In glaucoma, retinal ganglion cells (RGCs) die by apoptosis, generally attributed to an elevated intraocular pressure (IOP). We now describe the impact of elevated IOP in the rat on expression of caspase 8 and caspase 9, initiators of the extrinsic and intrinsic caspase cascades, respectively. Activ...

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Autors principals: Huang, Wei, Dobberfuhl, Adam, Filippopoulos, Theodoros, Ingelsson, Martin, Fileta, John B., Poulin, Nathaniel R., Grosskreutz, Cynthia L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2005
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Original Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698740/
https://ncbi.nlm.nih.gov/pubmed/16127148
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