Abnormalities of GATA-1 in Megakaryocytes from Patients with Idiopathic Myelofibrosis

The abnormal megakaryocytopoiesis associated with idiopathic myelofibrosis (IM) plays a role in its pathogenesis. Because mice with defective expression of transcription factor GATA-1 (GATA-1(low) mutants) eventually develop myelofibrosis, we investigated the occurrence of GATA-1 abnormalities in IM...

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Hauptverfasser: Vannucchi, Alessandro M., Pancrazzi, Alessandro, Guglielmelli, Paola, Di Lollo, Simonetta, Bogani, Costanza, Baroni, Gianna, Bianchi, Lucia, Migliaccio, Anna Rita, Bosi, Alberto, Paoletti, Francesco
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2005
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Original Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698737/
https://ncbi.nlm.nih.gov/pubmed/16127162
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