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Mapping Trait Loci by Use of Inferred Ancestral Recombination Graphs

Large-scale association studies are being undertaken with the hope of uncovering the genetic determinants of complex disease. We describe a computationally efficient method for inferring genealogies from population genotype data and show how these genealogies can be used to fine map disease loci and...

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Détails bibliographiques
Auteurs principaux: Minichiello, Mark J., Durbin, Richard
Format: Artigo
Langue:Inglês
Publié: The American Society of Human Genetics 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698562/
https://ncbi.nlm.nih.gov/pubmed/17033967
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