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Bursts of nonsynonymous substitutions in HIV-1 evolution reveal instances of positive selection at conservative protein sites
The fixation of a new allele can be driven by Darwinian positive selection or can be due to random genetic drift. Identifying instances of positive selection is a difficult task, because its impact is routinely obscured by the action of negative selection. The nature of the genetic code dictates tha...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1698441/ https://ncbi.nlm.nih.gov/pubmed/17164328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609484103 |
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