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Use of Smear-Positive Samples To Assess the PCR-Based Genotype MTBDR Assay for Rapid, Direct Detection of the Mycobacterium tuberculosis Complex as Well as Its Resistance to Isoniazid and Rifampin

Isoniazid (INH) and rifampin (RIF) are two of the most important antituberculosis drugs, and resistance to both of these drugs can often result in treatment failure and fatal clinical outcome. Resistance to these two first-line drugs is most often attributed to mutations in the katG, inhA, and rpoB...

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Bibliografische gegevens
Hoofdauteurs: Somoskovi, Akos, Dormandy, Jillian, Mitsani, Dimitra, Rivenburg, Jeremy, Salfinger, Max
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698430/
https://ncbi.nlm.nih.gov/pubmed/17035488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01506-06
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