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SarA Is a Repressor of hla (α-Hemolysin) Transcription in Staphylococcus aureus: Its Apparent Role as an Activator of hla in the Prototype Strain NCTC 8325 Depends on Reduced Expression of sarS

In most Staphylococcus aureus strains, inactivation of sarA increases hla transcription, indicating that sarA is a repressor. However, in S. aureus NCTC 8325 and its derivatives, used for most studies of hla regulation, inactivation of sarA resulted in decreased hla transcription. The disparate phen...

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Detalhes bibliográficos
Main Authors: Oscarsson, Jan, Kanth, Anna, Tegmark-Wisell, Karin, Arvidson, Staffan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698246/
https://ncbi.nlm.nih.gov/pubmed/17012389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00866-06
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