Mycobacterium tuberculosis SigM Positively Regulates Esx Secreted Protein and Nonribosomal Peptide Synthetase Genes and Down Regulates Virulence-Associated Surface Lipid Synthesis

The Mycobacterium tuberculosis genome encodes 12 alternative sigma factors, several of which regulate stress responses and are required for virulence in animal models of acute infection. In this work we investigated M. tuberculosis SigM, a member of the extracytoplasmic function subfamily of alterna...

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Détails bibliographiques
Auteurs principaux: Raman, Sahadevan, Puyang, Xiaoling, Cheng, Tan-Yun, Young, David C., Moody, D. Branch, Husson, Robert N.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
Sujets:
Gene Regulation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698216/
https://ncbi.nlm.nih.gov/pubmed/17028284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01212-06
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