A Phase II Study of Flavopiridol in Patients With Previously Untreated Advanced Soft Tissue Sarcoma

Purpose. Flavopiridol is a potent cyclin-dependent kinase (CDK) inhibitor that has preclinical activity in many tumours. This synthetic flavonoid was tested in a phase II nonrandomized, nonblinded multicentre clinical trial to determine its activity and toxicity in patients with previously untreated...

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Autori principali: Morris, Don G., Bramwell, Vivien H. C., Turcotte, Robert, Figueredo, Alvaro T., Blackstein, Martin E., Verma, Shail, Matthews, Sarah, Eisenhauer, Elizabeth A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2006
Soggetti:
Clinical Study
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698142/
https://ncbi.nlm.nih.gov/pubmed/17251659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/SRCM/2006/64374
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