Surfactant Protein D Increases Fusion of Mycobacterium tuberculosis- Containing Phagosomes with Lysosomes in Human Macrophages

Lung surfactant protein D (SP-D) binds to Mycobacterium tuberculosis surface lipoarabinomannan and results in bacterial agglutination, reduced uptake, and inhibition of growth in human macrophages. Here we show that SP-D limits the intracellular growth of bacilli in macrophages by increasing phagoso...

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Detalhes bibliográficos
Main Authors: Ferguson, J. Scott, Martin, Jennifer L., Azad, Abul K., McCarthy, Travis R., Kang, Peter B., Voelker, Dennis R., Crouch, Erika C., Schlesinger, Larry S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698096/
https://ncbi.nlm.nih.gov/pubmed/17030585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01402-06
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