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Charge Delocalization in Proton Channels, II: The Synthetic LS2 Channel and Proton Selectivity

In this study, the minimalist synthetic LS2 channel is used as a prototype to examine the selectivity of protons over other cations. The free-energy profiles along the transport pathway of LS2 are calculated for three cation species: a realistic delocalized proton (including Grotthuss shuttling)—H(+...

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Detalhes bibliográficos
Main Authors: Wu, Yujie, Ilan, Boaz, Voth, Gregory A.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1697870/
https://ncbi.nlm.nih.gov/pubmed/17056732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.091942
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