Role of lgtC in Resistance of Nontypeable Haemophilus influenzae Strain R2866 to Human Serum

We are investigating a nontypeable Haemophilus influenzae (NTHI) strain, R2866, isolated from a child with meningitis. R2866 is unusually resistant to killing by normal human serum. The serum 50% inhibitory concentration (IC(50)) for this strain is 18%, approaching that of encapsulated H. influenzae...

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Main Authors: Erwin, Alice L., Allen, Simon, Ho, Derek K., Bonthius, Paul J., Jarisch, Justin, Nelson, Kevin L., Tsao, David L., Unrath, William C. T., Watson, Michael E., Gibson, Bradford W., Apicella, Michael A., Smith, Arnold L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2006
Teme:
Molecular Pathogenesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1695526/
https://ncbi.nlm.nih.gov/pubmed/16966407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00722-06
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