Complex Role of Hemoglobin and Hemoglobin-Haptoglobin Binding Proteins in Haemophilus influenzae Virulence in the Infant Rat Model of Invasive Infection

Haemophilus influenzae requires an exogenous heme source for aerobic growth in vitro. Hemoglobin or hemoglobin-haptoglobin satisfies this requirement. Heme acquisition from hemoglobin-haptoglobin is mediated by proteins encoded by hgp genes. Both Hgps and additional proteins, including those encoded...

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Detalhes bibliográficos
Main Authors: Seale, Thomas W. , Morton, Daniel J., Whitby, Paul W., Wolf, Roman, Kosanke, Stanley D., VanWagoner, Timothy M., Stull, Terrence L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1695506/
https://ncbi.nlm.nih.gov/pubmed/16966415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00744-06
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