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The melanocyte differentiation program predisposes to metastasis following neoplastic transformation.
The aggressive clinical behavior of melanoma has led to the hypothesis that the developmental origins of melanocytes in the neural crest might be relevant for their metastatic propensity. We demonstrate that primary human melanocytes, transformed using a specific set of introduced genes, form melano...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1694635/ https://ncbi.nlm.nih.gov/pubmed/16142232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng1634 |
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