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Acyl-Substituted Dermaseptin S4 Derivatives with Improved Bactericidal Properties, Including on Oral Microflora

The 15-mer dermaseptin S4 derivative S4(1-15) was recently shown to exhibit potent activity against oral pathogens associated with caries and periodontitis. Here, we investigated possible modes for improving the peptide's properties through systematic replacement of an N-terminal amino acid(s)...

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Hlavní autoři: Porat, Y., Marynka, K., Tam, A., Steinberg, D., Mor, A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693992/
https://ncbi.nlm.nih.gov/pubmed/17043126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00750-06
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