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Novel Alpha Interferon (IFN-α) Variant with Improved Inhibitory Activity against Hepatitis C Virus Genotype 1 Replication Compared to IFN-α2b Therapy in a Subgenomic Replicon System

Hepatitis C virus (HCV) treatment is based on the association of pegylated alpha interferon (IFN-α) and ribavirin. To improve the level of sustained virological response to treatment, especially in patients infected with HCV genotype 1, new IFNs with improved efficacy and toxicity profiles may be de...

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Detalhes bibliográficos
Main Authors: Escuret, Vanessa, Martin, Amaury, Durantel, David, Parent, Romain, Hantz, Olivier, Trépo, Christian, Menguy, Thierry, Bottius, Emmanuel, Dardy, Jerome, Maral, Jean, Escary, Jean Louis, Zoulim, Fabien
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693984/
https://ncbi.nlm.nih.gov/pubmed/17030563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00199-06
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