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The mechanism of gene targeting in Physcomitrella patens: homologous recombination, concatenation and multiple integration

The model bryophyte Physcomitrella patens exhibits high frequencies of gene targeting when transformed with DNA constructs containing sequences homologous with genomic loci. ‘Targeted gene replacement’ (TGR) resulting from homologous recombination (HR) between each end of a targeting construct and t...

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Detalhes bibliográficos
Main Authors: Kamisugi, Yasuko, Schlink, Katja, Rensing, Stefan A., Schween, Gabriele, von Stackelberg, Mark, Cuming, Andrew C., Reski, Ralf, Cove, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693892/
https://ncbi.nlm.nih.gov/pubmed/17090599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl832
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