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Using optical tweezers to relate the chemical and mechanical cross-bridge cycles.

In most current models of muscle contraction there are two translational steps, the working stroke, whereby an attached myosin cross-bridge moves relative to the actin filament, and the repriming step, in which the cross-bridge returns to its original orientation. The development of single molecule...

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Autors principals: Steffen, Walter, Sleep, John
Format: Artigo
Idioma:Inglês
Publicat: 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693469/
https://ncbi.nlm.nih.gov/pubmed/15647161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2004.1558
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