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The N-methyl D-aspartate receptor glycine site and D-serine metabolism: an evolutionary perspective.
The N-methyl D-aspartate (NMDA) type of glutamate receptor requires two distinct agonists to operate. Glycine is assumed to be the endogenous ligand for the NMDA receptor glycine site, but this notion has been challenged by the discovery of high levels of endogenous d-serine in the mammalian forebra...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1693380/ https://ncbi.nlm.nih.gov/pubmed/15306409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2003.1399 |
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