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Biochemistry of glycosphingolipid storage disorders: implications for therapeutic intervention.

The physiological importance of the degradative processes in lysosomes is revealed by the existence of at least 40 distinct inherited diseases, the so-called lysosomal storage disorders. Most of these diseases are caused by a deficiency in a single lysosomal enzyme, or essential cofactor, and result...

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Detalhes bibliográficos
Main Authors: Aerts, Johannes M, Hollak, Carla, Boot, Rolf, Groener, Ans
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693181/
https://ncbi.nlm.nih.gov/pubmed/12803924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2003.1273
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