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The role of thermal activation in motion and force generation by molecular motors.

The currently accepted mechanism for ATP-driven motion of kinesin is called the hand-over-hand model, where some chemical transition during the ATP hydrolysis cycle stretches a spring, and motion and force production result from the subsequent relaxation. It is essential in this mechanism for the mo...

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Detalhes bibliográficos
Autor principal: Astumian, R D
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1692764/
https://ncbi.nlm.nih.gov/pubmed/10836504
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