Ca(2+)-dependent regulation of synaptic SNARE complex assembly via a calmodulin- and phospholipid-binding domain of synaptobrevin

Synaptic core complex formation is an essential step in exocytosis, and assembly into a superhelical structure may drive synaptic vesicle fusion. To ascertain how Ca(2+) could regulate this process, we examined calmodulin binding to recombinant core complex components. Surface plasmon resonance and...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Quetglas, Stephanie, Leveque, Christian, Miquelis, Raymond, Sato, Kazuki, Seagar, Michael
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2000
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16927/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10944231/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.17.9695
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