Identification of type II restriction and modification systems in Helicobacter pylori reveals their substantial diversity among strains

A total of 22 type II restriction endonucleases with 18 distinct specificities have been identified in six Helicobacter pylori strains. Among these 18 specificities are three completely new endonucleases, Hpy178III, Hpy99I, and Hpy188I, that specifically cleave DNA at TCNNGA, CGWCG, and TCNGA sites,...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Xu, Qing, Morgan, Richard D., Roberts, Richard J., Blaser, Martin J.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2000
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16923/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10944229/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.17.9671
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