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Telomere shortening impairs organ regeneration by inhibiting cell cycle re-entry of a subpopulation of cells
Telomere shortening limits the regenerative capacity of primary cells in vitro by inducing cellular senescence characterized by a permanent growth arrest of cells with critically short telomeres. To test whether this in vitro model of cellular senescence applies to impaired organ regeneration induce...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC169040/ https://ncbi.nlm.nih.gov/pubmed/12881434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg367 |
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