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Normotonic cell shrinkage because of disordered volume regulation is an early prerequisite to apoptosis

A major hallmark of apoptosis is normotonic shrinkage of cells. Here, we studied the relation between apoptotic cell shrinkage and apoptotic cell death. Induction of the apoptotic volume decrease (AVD) under normotonic conditions was found to be coupled to facilitation of the regulatory volume decre...

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Detalhes bibliográficos
Main Authors: Maeno, Emi, Ishizaki, Yasuki, Kanaseki, Toku, Hazama, Akihiro, Okada, Yasunobu
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16891/
https://ncbi.nlm.nih.gov/pubmed/10900263
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