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Modelling the activation, opening, inactivation and reopening of the voltage-gated sodium channel.

A model of the voltage-gated sodium channel is put forward suggesting that the four S4 voltage-sensors behave as screw-helices making a series of discrete transitions that carry one elementary charge for each notch of the screw helix. After the channel has been activated by the first two steps R in...

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Main Authors: Keynes, R D, Elinder, F
格式: Artigo
語言:Inglês
出版: 1998
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1688889/
https://ncbi.nlm.nih.gov/pubmed/9523428
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