The histone variant mH2A1.1 interferes with transcription by down-regulating PARP-1 enzymatic activity

The histone variant mH2A is believed to be involved in transcriptional repression, but how it exerts its function remains elusive. By using chromatin immunoprecipitation and tandem affinity immunopurification of the mH2A1.1 nucleosome complex, we identified numerous genes with promoters containing m...

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Bibliographic Details
Main Authors: Ouararhni, Khalid, Hadj-Slimane, Réda, Ait-Si-Ali, Slimane, Robin, Philippe, Mietton, Flore, Harel-Bellan, Annick, Dimitrov, Stefan, Hamiche, Ali
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2006
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1686608/
https://ncbi.nlm.nih.gov/pubmed/17158748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.396106
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