The histone variant mH2A1.1 interferes with transcription by down-regulating PARP-1 enzymatic activity

The histone variant mH2A is believed to be involved in transcriptional repression, but how it exerts its function remains elusive. By using chromatin immunoprecipitation and tandem affinity immunopurification of the mH2A1.1 nucleosome complex, we identified numerous genes with promoters containing m...

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Detalhes bibliográficos
Main Authors: Ouararhni, Khalid, Hadj-Slimane, Réda, Ait-Si-Ali, Slimane, Robin, Philippe, Mietton, Flore, Harel-Bellan, Annick, Dimitrov, Stefan, Hamiche, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1686608/
https://ncbi.nlm.nih.gov/pubmed/17158748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.396106
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