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A simple function for maternal-age-specific rates of Down syndrome in the 20-to-49-year age range and its biological implications.

The familial increase in the rate of Down syndrome with maternal age can be represented by a simple equation, consisting of the sum of a constant term plus an exponential term that is a first-order function of masternal age: y = a + exp (b + cx), where y is the rate in live births, x is maternal age...

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Detalhes bibliográficos
Main Authors: Lamson, S H, Hook, E B
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1686092/
https://ncbi.nlm.nih.gov/pubmed/6448545
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