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Estimating sex ratio biases in X-linked disorders: is there an excess of males in families with X-linked ichthyosis?

We derive the conditional probabilities for estimating the sex ratio in families ascertained through affected males for the study of X-linked recessive diseases. These conditional probabilities correct for the fact that the probability that a family will be ascertained increases with the number of m...

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Autori principali: Gladstien, K, Shapiro, L J, Spence, M A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1979
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1686026/
https://ncbi.nlm.nih.gov/pubmed/517522
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