Spinophilin regulates the formation and function of dendritic spines

Spinophilin, a protein that interacts with actin and protein phosphatase-1, is highly enriched in dendritic spines. Here, through the use of spinophilin knockout mice, we provide evidence that spinophilin modulates both glutamatergic synaptic transmission and dendritic morphology. The ability of pro...

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Bibliografiske detaljer
Main Authors: Feng, Jian, Yan, Zhen, Ferreira, Adriana, Tomizawa, Kazuhito, Liauw, Jason A., Zhuo, Min, Allen, Patrick B., Ouimet, Charles C., Greengard, Paul
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC16860/
https://ncbi.nlm.nih.gov/pubmed/10922077
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