Kinetic analysis of genetic complementation in heterokaryons of propionyl CoA carboxylase-deficient human fibroblasts.

We studied genetic complementation of propionyl CoA carboxylase (PCC) deficiency in cultures of polyethylene glycol (PEG)-induced heterokaryons, using mutant fibroblast lines assigned to five mutant classes, designated bio, pcc A, pcc B, pcc C, and pcc BC. By measuring PCC activity directly in extra...

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Bibliographic Details
Main Authors: Wolf, B, Willard, H F, Rosenberg, L E
Format: Artigo
Language:Inglês
Published: 1980
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1685923/
https://ncbi.nlm.nih.gov/pubmed/7361761
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