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Structural difference at the active site of dibucaine resistant variant of human plasma cholinesterase.

Human plasma cholinesterase from five different genotypes -- E1U E1U, E1U E1A, E1A E1A, E1U E1S, E1A E1S, and E1U E1U C5+ -- was purified 8,000 fold from serum by a two-step procedure involving chromatography on DEAE-cellulose and preparative disc electrophoresis. The esterases were labeled with dii...

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Bibliografske podrobnosti
Main Authors: Muensch, H, Yoshida, A, Altland, K, Jensen, W, Goedde, H W
Format: Artigo
Jezik:Inglês
Izdano: 1978
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1685588/
https://ncbi.nlm.nih.gov/pubmed/677127
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