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Evidence for a major dominance component in the variation of serum pepsinogen I levels

We report here a variance component analysis of the distribution of serum pepsinogen I levels in normal individuals, using a maximum-likelihood method on entire pedigrees. The results indicate a broad heritability of 91%, with some 74% being attributed to a dominance component. This is consistent wi...

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Autors principals: Rotter, J. I., Wong, F. L., Samloff, I. M., Varis, K., Siurala, M., Ihamaki, T., Ellis, A., McConnell, R. B.
Format: Artigo
Idioma:Inglês
Publicat: 1982
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1685324/
https://ncbi.nlm.nih.gov/pubmed/7081219
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