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Physical mapping around the Alzheimer disease locus on the proximal long arm of chromosome 21.

Evidence from linkage studies suggests that familial Alzheimer disease (AD) can be caused by a defect in a gene on the proximal long arm of chromosome 21. We have constructed a physical map spanning 10 megabases of this region of the chromosome by means of pulsed-field gel electrophoresis and analys...

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Detalhes bibliográficos
Main Authors: Owen, M J, James, L A, Hardy, J A, Williamson, R, Goate, A M
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1684974/
https://ncbi.nlm.nih.gov/pubmed/2301399
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