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Linkage strategies for genetically complex traits. III. The effect of marker polymorphism on analysis of affected relative pairs.
The results from the second paper of this series are reexamined for markers that are not completely polymorphic. A maximum lod score (MLS) criterion is defined for affected relative pairs. The expected MLS (EMLS) is calculated as a function of the marker polymorphic information content (PIC) for var...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1684966/ https://ncbi.nlm.nih.gov/pubmed/2301394 |
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