A systematic approach for detecting high-frequency restriction fragment length polymorphisms using large genomic probes.

Thirteen phage clones containing low-copy sequences were isolated from a human DNA library and tested for their ability to detect restriction fragment length polymorphisms (RFLPs). Reported are the RFLPs revealed with each clone, all found in frequencies useful for linkage studies. Cytological data...

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Main Authors: Feder, J, Yen, L, Wijsman, E, Wang, L, Wilkins, L, Schroder, J, Spurr, N, Cann, H, Blumenberg, M, Cavalli-Sforza, L L
Format: Artigo
Jezik:Inglês
Izdano: 1985
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1684621/
https://ncbi.nlm.nih.gov/pubmed/9556655
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