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Toward a complete linkage map of the human X chromosome: regional assignment of 16 cloned single-copy DNA sequences employing a panel of somatic cell hybrids.

Closely linked restriction fragment length polymorphisms (RFLPs) are potentially useful as diagnostic markers of genetic defects, and, in principle, RFLPs can be employed to construct a complete linkage map of the human genome. On the X chromosome, linkage studies are particularly rewarding because...

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Main Authors: Wieacker, P, Davies, K E, Cooke, H J, Pearson, P L, Williamson, R, Bhattacharya, S, Zimmer, J, Ropers, H H
Formato: Artigo
Idioma:Inglês
Publicado: 1984
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1684417/
https://ncbi.nlm.nih.gov/pubmed/6324578
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