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Detection of multiallele polymorphisms within gene sequences by GC-clamped denaturing gradient gel electrophoresis.

The ability to efficiently detect DNA polymorphisms is essential for the completion of a high-resolution polymorphic linkage map of the human genome. Currently the most informative polymorphisms are the multiallelic dinucleotide repeat polymorphisms. However, many gene sequences lack an associated d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sheffield, V C, Beck, J S, Nichols, B, Cousineau, A, Lidral, A C, Stone, E M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1684270/
https://ncbi.nlm.nih.gov/pubmed/1539594
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