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Biochemical characterisation of LigN, an NAD(+)-dependent DNA ligase from the halophilic euryarchaeon Haloferax volcanii that displays maximal in vitro activity at high salt concentrations

BACKGROUND: DNA ligases are required for DNA strand joining in all forms of cellular life. NAD(+)-dependent DNA ligases are found primarily in eubacteria but also in some eukaryotic viruses, bacteriophage and archaea. Among the archaeal NAD(+)-dependent DNA ligases is the LigN enzyme of the halophil...

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Main Authors: Poidevin, Laetitia, MacNeill, Stuart A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1684257/
https://ncbi.nlm.nih.gov/pubmed/17132163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-7-44
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