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SigFlux: A novel network feature to evaluate the importance of proteins in signal transduction networks

BACKGROUND: Measuring each protein's importance in signaling networks helps to identify the crucial proteins in a cellular process, find the fragile portion of the biology system and further assist for disease therapy. However, there are relatively few methods to evaluate the importance of prot...

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Bibliographic Details
Main Authors: Liu, Wei, Li, Dong, Zhang, Jiyang, Zhu, Yunping, He, Fuchu
Format: Artigo
Language:Inglês
Published: BioMed Central 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1683949/
https://ncbi.nlm.nih.gov/pubmed/17129367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-515
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