Analysis of DNA polymorphisms suggests that most de novo dup(21q) chromosomes in patients with Down syndrome are isochromosomes and not translocations.

類似資料

• Down syndrome due to de novo Robertsonian translocation t(14q;21q): DNA polymorphism analysis suggests that the origin of the extra 21q is maternal.
  著者:: Petersen, M B, 等
  出版事項: (1991)
• Parental mosaicism in de novo translocation (21q21q) Down's syndrome.
  著者:: Croci, G, 等
  出版事項: (1991)
• Sibship (21q21q) Translocation Down's Syndrome with Maternal Transmission
  著者:: Furbetta, M., 等
  出版事項: (1973)
• No evidence for a paternal interchromosomal effect from analysis of the origin of nondisjunction in Down syndrome patients with concomitant familial chromosome rearrangements.
  著者:: Schinzel, A A, 等
  出版事項: (1992)
• Interstitial deletion, del(4)(q12q21.1), owing to de novo unbalanced translocation in a 2 year old girl: further evidence that the piebald trait maps to proximal 4q12.
  著者:: Schinzel, A, 等
  出版事項: (1997)