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The probabilistic determination of identity-by-descent sharing for pairs of relatives from pedigrees.

Methods for detecting genetic linkage are more powerful when they fully use all of the data collected from pedigrees. We first discuss a method for obtaining the probability that a pedigree member has a given genotype, conditional on the phenotypes of his relatives. We then develop a rapid method to...

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Bibliografski detalji
Glavni autori: Amos, C I, Dawson, D V, Elston, R C
Format: Artigo
Jezik:Inglês
Izdano: 1990
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1683683/
https://ncbi.nlm.nih.gov/pubmed/2220824
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