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Methylation status of genes flanking the fragile site in males with the fragile-X syndrome: a test of the imprinting hypothesis.

Laird has suggested that the mutation responsible for the fragile X (FraX) syndrome interferes with the process of X chromosome reactivation in oocytes, thus blocking the transcription of loci at or neighboring the fragile site (Xq27.3) and producing the clinical FraX phenotype; he has also suggeste...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Khalifa, M M, Reiss, A L, Migeon, B R
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1990
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1683650/
https://ncbi.nlm.nih.gov/pubmed/2316521
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